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A Reading List for Quantitative and Population Genetics: From Fisher to Modern Plant Breeding

·377 words·2 mins
Wenbin Mei, PhD
Author
Wenbin Mei, PhD
Computational biology and AI leader in genomics, machine learning, and genome editing.

My PhD focused on genomics and bioinformatics, so when I moved into population genomics as a postdoc in Jeffrey Ross-Ibarra’s lab, I spent a lot of time strengthening my foundation in quantitative and population genetics, building on what I had learned at the Summer Institute in Statistical Genetics. This list collects the books, lecture notes and classic papers that helped me most. The two fields share the same roots: in the 1920s and 1930s, Fisher, Wright and Haldane reconciled Mendelian inheritance with Darwin’s natural selection, and their ideas still underpin how we map traits, estimate heritability and predict breeding values today. Population genetics explains how mutation, drift, selection and migration shape variation in genomes; quantitative genetics connects that variation to complex traits and is the statistical engine behind modern plant breeding, from mixed models to genomic selection. I have grouped the resources into quantitative genetics, population genetics and the classic texts, with links to free online versions where they exist.

Quantitative genetics
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Population genetics
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Classic books
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Updated October 2026: links checked, and dead links replaced with publisher pages or archived copies.