Functional Space Hypothesis - different adapation pattern between small and large genomes

This project we proposed the functional space hypothesis and we argue that big genomes adaptive differently compared to small genomes. Large genome utilize more beneficial mutation from regulatory sequence far away from genes, implications for soft sweeps, standing variation et al.

Alternative Splicing in Maize

This project depicts the complexity alternative splicing landscape in maize. We surveyed the alternative splicing catelogs in different tissues, between genotypes and during seed development, in addition, we mapped the cis- and trans- splicing QTL and examined the fate of alternative splicing after whole genome duplication compared to sorghum.

Identify functional constraint alternative splicing across species

This project focuses on identified functional constraint alternative splicing across grass genomes. This work is recently published as Cover story in GENETICS. The cover is Amborella used as outgroup in the analysis.

Population genetics of structural variation in maize and teosinte

This project focuses on population genetics of structural variation (inversion and copy number variation) in maize and teosinte.


(in revision)

(in revision)

American Journal of Botany (2018)

Genetics (2017)

Current Biology (2017)

Molecular Ecology Resources (2017)

Frontiers in Plant Science (2017)

Genome Biology and Evolution (2017)

Proceedings of the National Academy of Sciences (2017)

Molecular Ecology Resource (2015)

American Journal of Physiology - Regulatory, Integrative and Comparative Physiology (2014)

BMC Plant Biology (2014)

New Phytologist (2014)

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology (2014)

Compendium of Bioenergy Plants: Corn (2014)

Science (2013)

Molecular biology and evolution (2013)

Thesis (M.S. 2010) – Central Washington University

Blog Posts

Here is a collection of resource and notes about quantative genetics and population genetics.


Here I collect some resources for people interested in learning R, Python and Perl.


Recent I gave a talk about my PhD work at Chinese Genomics online Meet-up.